The differences in VEP (Visual Evoked Potentials) between epileptics and normal subjects
Koyama, Kyo The University of Tokushima
Nakayama, Hiroshi The University of Tokushima
Okura, Masao The University of Tokushima
Ikuta, Takumi The University of Tokushima
Kawamura, Ichiro The University of Tokushima
The differences between epileptics and healthy subjects on the visual evoked potential (VEP) were studied. VEPs were recorded through the two derivations (2 ch : O 1→A 1+2, 5 ch : O 1→Cz). The differences in the latencies and interpeak amplitudes were compared and tested statistically, respectively for each sex, with special reference to the drugs been administered.
1. The latencies of VEP components in epileptics were longer than those in healthy subjects, in both sexes.
2. Interpeak amplitudes of VEP components in epileptics were smaller than those in healthy subjects, especially in late components, in both sexes.
3. These tendencies were more marked in males than in females.
4. In epileptics, between the subjects being administered each drug (CBZ, PB, VPA or PHT) or not, significant differences in latencies and intrerpeak amplitudes were not confirmed, with the components in which significant differences in latencies and amplitudes between epileptics and healthy subjects were found.
We verified the significant differences in VEPs between epileptics and healthy subjects, which suggested the dysfunction in epileptics in its brain stem and lateral geniculate body, even not considering the seizure types nor epileptic focus sites.
Shikoku Acta Medica
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