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ID 117127
Title Alternative
Predicting future onset of metabolic syndrome by the serum level of total adiponectin
メタボ対策に応用できるアディポネクチン測定
Author
Keywords
Adiponectin
Metabolic syndrome
Cut-off value
Content Type
Journal Article
Description
A rapid increase in the number of people who develop metabolic syndrome(MetS)is drawing much attention, since MetS-associated complications, such as cardiovascular diseases, are not only life-threatening, but also remarkably impair the quality of life for those who have MetS. Thus, developing a method to identify those who are at risk of developing MetS is crucial to maintain their quality of life and reduce the burden on society to provide care, since such a method will enable early intervention for those who may be at risk and prevent them from developing MetS. Here we report from two prospective cohort studies that the cut-off value of serum total adiponectin level for managing the risk of developing MetS is6.2μg/ml in male and6.5μg/ml in female. Subjects with total adiponectin level equal to or lower than the cut-off value developed MetS more rapidly than did those with total adiponectin level higher than the cut-off value. A follow up study validated the cutoff value of total adiponectin level in both male and female. Furthermore, evaluating the risk of developing MetS in future by adiponectin level successfully identified those who are at risk among people who are not obese by their anthropometric measurements. These results provide evidence that adiponectin level is able to serve as a biomarker for predicting future onset of MetS.
Journal Title
Shikoku Acta Medica
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
77
Issue
5-6
Start Page
181
End Page
186
Sort Key
181
Published Date
2021-12-25
FullText File
language
jpn
TextVersion
Publisher
departments
University Hospital