非歯原性歯痛の発症機序，診断，治療

Nonodontogenic toothache is a painful condition that occurs in the absence of any pathophysiological problems in the tooth or periodontal tissue. Nonodontogenic toothache has not been given adequate attention in undergraduate student education, and there is little information on diagnosis or management. The Japanese Society of Orofacial Pain published clinical practice guidelines for nonodontogenic toothache in 2012. These guidelines introduce nonodontogenic toothache and provide basic information on orofacial pain. In this review, electronic databases were used to search and assess the most reliable scientific evidence. Publications with a high evidence level, according to the nonodontogenic toothache guidelines, were selected and evaluated. This review encompasses all facets of clinical practice, ranging from basic scientific knowledge to therapeutic strategies, and targets all medical personnel involved in dental treatment. This review should be given due consideration by clinical personnel, and is anticipated to contribute to improving the quality of life of patients who suffer from nonodontogenic toothache.