膵がんについて : 診断と治療のトピックス

Pancreatic cancer is the fourth leading cause of cancer death in Japan and the incidence and mortality rates have been increasing year by year. Despite the significant progress has been made in management of pancreatic cancer, further preclinical and clinical research studies are needed to advance our clinical approach to this aggressive cancer. Recent advance in diagnostic modalities including MDCT, MRCP and EUS-FNA allow early detection and accurate preoperative staging of the disease. Although surgery remains the only curative treatment for pancreatic cancer, increasing evidence now suggest that further significant improvements to overall survival can be achieved via new chemotherapeutic options such as FOLFIRINOX and gemcitabine/nabpaclitaxel regimen. This review will provide an overview of clinical practice for pancreatic cancer.