ID 110403
タイトルヨミ
テンイソウ デ ホルモン ジュヨウタイ ノ ヘンイ オ ミトメタ ニュウガン ノ 1レイ
タイトル別表記
A case of breast cancer with conversion of estrogen and progesterone receptor expresson in metastatic lesion
著者
開野, 友佳理 医療法人倚山会田岡病院乳腺甲状腺科
沖津, 奈都 医療法人倚山会田岡病院乳腺甲状腺科
三木, 仁司 医療法人倚山会田岡病院乳腺甲状腺科
森本, 忠興 医療法人倚山会田岡病院乳腺甲状腺科 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
breast cancer
hormone receptor
receptor conversion
metastatic lesion
資料タイプ
学術雑誌論文
抄録
A 44 year old woman visited the hospital with complaint of the right breast tumor which she left for two years. She presented with a large mass of8.5cm in diameter with skin invasion, right axillar lymph nodes, multiple liver, and bone metastases. Core needle biopsy of the main tumor revealed an invasive ductal carcinoma(scirrhous carcinoma)with nuclear grade 2 with ER(+),PgR(+), HER2(-). The patient was treated with hormone therapy for three and a half year.The extensive mediastinum lymph nodes metastasis and multiple lung metastasis and a new tumor in the right thyroid lobe were appeared. The liver metastasis also increased in size and number.The therapy switched to chemotherapy with paclitaxel. Although the reductive effect was appeared in the breast mass, lung metastasis and liver metastasis, the thyroid and mediastinal lymph node metastases increased in size aggressively. The cytology of needle biopsy specimen from the thyroid tumor was consistent with breast cancer metastasis. Histopathology of the biopsy specimens from the mediastinal lymph node and the liver metastases also consist with breast cancer metastases, but ER and PgR receptor status converted to negative in mediastinal lymph nodes.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
72
5-6
開始ページ
199
終了ページ
204
並び順
199
発行日
2016-12-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
医学系