トウケイブ ヘンペイジョウヒガン ニ タイスル ガイライ カガク リョウホウ : カルボプラチン ト UFT ノ ヘイヨウ リョウホウ
Cancer chemotherapy for outpatients to the patients with head and neck squamous cell carcinoma : conbination therapy of carboplatin and UFT
堀, 洋二 徳島赤十字病院耳鼻咽喉科
加島, 健司 徳島赤十字病院耳鼻咽喉科
cancer chemotherapy for outpatients
head and neck cancer
We practiced the combination therapy of carboplatin (CBDCA) and UFT for the patients with head and neck cancer. It was given to 5 patients for adjuvant after first line therapy and also given 3 patients with recurrrence. CBDCA (450mg/body) was given i.v. at day 1, and UFT (400mg/day) was given p.o. from day 7 to day 28 repeatedly. The result was that 2 patients were obtained NC. The side effects of more than grade 3 were observed in 2 patients, whose AUC were calculated over 5, retrospectively. The combination therapy with CBDCA and UFT that can be given to outpatients may be useful for adjuvant chemotherapy or salvage chemotherapy to increase the quality of life.
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