ID 111505
著者
Fujimoto, Sayuri The University of Tokushima
Nomura, Masahiro The University of Tokushima
Niki, Miyako Okinosu Hospital
Motoba, Hideki The University of Tokushima
Ieishi, Kiyoshi The University of Tokushima
Mori, Toshifumi The University of Tokushima
Ikefuji, Hiroyuki The University of Tokushima
キーワード
chromogranin A
mental stress
gastrointestinal endoscopy
stress
elderly patient
資料タイプ
学術雑誌論文
抄録
Objective : Salivary chromogranin A (CgA) was recently reported to be a useful marker of mental stress. In this study, mental stress during upper gastrointestinal endoscopy was evaluated by measuring salivary CgA levels in young and elderly subjects. Methods : The subjects were 9 healthy subjects aged less than 50 years (young group) and 15 subjects aged 70 years or older (elderly group). The heart rate, blood pressure, blood oxygen saturation level, and salivary CgA concentration were measured before and after upper gastrointestinal endoscopy and compared. Results : In the young group, the CgA level decreased significantly (p<0.05) during endoscopy compared with the level during rest before endoscopy. In the elderly group, it also decreased significantly (p<0.05) during endoscopy compared with the level during rest before endoscopy. However, CgA levels were significantly higher (p<0.05) in the elderly group than in the young group both before and during endoscopy. The decrease in CgA levels was significantly greater (p<0.05) in the young group than in the elderly group. Conclusions : In this study, mental stress associated with endoscopy appears to be higher in elderly subjects than in younger subjects. Attention to complications due to increased stress is considered to be necessary in elderly patients during endoscopy.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
54
1-2
開始ページ
140
終了ページ
145
並び順
140
発行日
2007-02
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系