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ID 111625
タイトル別表記
自閉症スペクトラム障害における近赤外線スペクトロスコピーを用いた表情認知機能の評価
著者
古川, 薫 徳島大学大学院保健科学教育部(保健学専攻)
キーワード
Autism Spectrum Disorder
Near-Infrared Spectroscopy
Autism-Spectrum Quotient
Facial Expression Recognition
Prefrontal Cortex
資料タイプ
学位論文
抄録
One of the characteristics of Autism Spectrum Disorder (ASD) is social disorder. The specificity of facial and expression recognition for people with ASD is gathering attention as a factor of this social disorder. The study examined the hemodynamic activities in the prefrontal cortex using near-infrared spectroscopy (NIRS) when a person with ASD performed an expression recognition task. The subjects were twenty males (18 - 22 years old) with ASD and without intellectual disabilities. Forty-five healthy males matched for age and sex were included as a control group. In both groups, the degree of autistic tendencies was evaluated using the Autism-Spectrum Quotient (AQ). Using eight standard emotional expressions of Japanese people, two expression recognition tasks were set. An NIRS was used to measure the prefrontal cortex blood mobilization during the expression-processing process. The AQ was significantly higher in the ASD group, while the rate of overall correct expression response was significantly lower (p < 0.001). A negative correlation was found when the relationship between the AQ and the rate of overall correct expression response was evaluated by combining the results of the control group with those of the ASD group (ρ = −0.40 p < 0.001). In the automatic expression-processing task, no activation in the prefrontal cortex was found in either the ASD or the control group. In the conscious expression-processing task, the activation of the left and right lateral prefrontal cortex was weaker in the ASD group compared to the control group. Unlike in the control group, a mild activation of posterior prefrontal cortex was found in the ASD group. The expression-processing process of the ASD group was found to be different from that of the control group. NIRS was effective in detecting a brain function disorder in people with ASD during an expression-processing process.
掲載誌名
Open Journal of Psychiatry
ISSN
21617325
21617333
出版者
Scientific Research Publishing
8
1
開始ページ
35
終了ページ
49
発行日
2017-12-20
備考
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Kaoru Furukawaの学位論文として提出され, 学位審査・授与の対象となっている。
権利情報
© 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3151号
学位記番号
甲保第31号
学位授与年月日
2018-02-22
学位名
博士(保健学)
学位授与機関
徳島大学
部局
医学系