ID 112084
タイトル別表記
Blink reflex excitability recovery curves in patients with dysfunctions after facial nerve palsy
顔面神経麻痺後遺症患者の瞬目反射回復曲線
著者
加島, 健司 徳島大学
キーワード
facial palsy
sequelae
blink reflex
excitability recovery curve
資料タイプ
学術雑誌論文
抄録
Postparalytic facial dysfunctions (PPFD) such as associate movements, crocodile tears and facial contracture are well-known sequelae of peripheral facial nerve palsy. The physiological basis for those disturbing conditions are unknown. Peripheral hypothesis such as misdirection theory or ephaptic transmission theory have been widely accepted.
On the other hand, some investigators made the hypothesis that hyperexcitability of the facial motoneurons had some contribution to the onset of the PPFD. A few physiological studies indicated the evidence of hyperexcitability of the facial motoneurons, however, there is not enough evidence of physiological changes in the nuclear or supranuclear system in patients with PPFD. Therefore, the blink reflex excitability recovery curves were studied in 10 patients with PPFD and 10 healthy control subjects to detect if physiological changes had occurred in the patients with PPFD. The inhibitory effects of the conditioning stimuli on the ipsilateral R 2 (iR 2) and contralateral R 2 (cR 2) responses observed in normal controls were significantly less in patients with PPFD. The results of this study indicate that patients with PPFD have increased excitability of central interneurons which mediate the R 2 pathway. We suggest that not only changes in the peripheral facial nerve but also changes in the central nervous system may contribute to the onset of PPFD.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
54
3
開始ページ
251
終了ページ
256
並び順
251
発行日
1998-06-25
フルテキストファイル
言語
jpn
著者版フラグ
出版社版