ID 112872
著者
板東, 浩 Tokushima University|Japan Low Carbohydrate Diet Promotion Association KAKEN研究者をさがす
Ebe, Koji Japan Low Carbohydrate Diet Promotion Association|Takao Hospital
Muneta, Tetsuo Japan Low Carbohydrate Diet Promotion Association|Muneta Maternity Clinic
Bando, Masahiro Tokushima University
Yonei, Yoshikazu Doshisha University
キーワード
Fasting ratio of C-peptide/glucose
Calorie Restriction (CR)
C-peptide (CP)
type 2 diabetes mellitus (T2DM)
C-peptide index (CPI)
資料タイプ
学術雑誌論文
抄録
Background: Authors have continued research concerning Low Carbohydrate Diet (LCD) and its related biomarkers. We also investigated correlation among several factors such as daily profile, fasting and average of blood glucose, Morbus value, and insulin and C-peptide.
Subjects and Methods: Subjects were patients with type 2 diabetes mellitus (T2DM), classified into three groups due to HbA1c value. Methods included 1) basal blood exams, 2) intake of Calorie Restriction (CR) meal with 1400kcal/day with 60% of carbohydrates, 3) check of daily blood glucose 7 times a day, 4) calculation of average glucose and M value, 5) analyses of biomarkers.
Results: Average blood glucose was 168 mg/dL, 206 mg/dL, 265mg/dL in low, middle, high group, respectively. Fasting ratio of C-peptide/glucose in 3 groups was 0.37, 0.34, 0.26, respectively period. There was significant correlation among HbA1c, M value and fasting ratio of C-peptide/glucose.
Discussion and Conclusion: Among 3 groups, high group revealed lower tendency of fasting C-peptide and fasting ratio of C-peptide/glucose than other groups, suggesting that high group might has lower ability of insulin secretion. Fasting ratio of C-peptide/glucose would be useful for indicating beta cell function and predicting insulin requirement in clinical practice.
掲載誌名
Archives of Diabetes and Endocrine System
ISSN
26384981
出版者
Sryahwa Publications
1
1
開始ページ
17
終了ページ
24
発行日
2018
権利情報
© 2018 Hiroshi BANDO, Koji EBE, Tetsuo MUNETA, Masahiro BANDO, Yoshikazu YONEI. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系