直近一年間の累計
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ID 112967
著者
Munkhzaya, Munkhsaikhan Tokushima University
Tungalagsuvd, Altankhuu Tokushima University
Mayila, Yiliyasi Tokushima University
矢野, 清人 Tokushima University
Yanagihara, Rie Tokushima University
Tokui, Takako Tokushima University
キーワード
prenatal undernutrition
preputial separation
sexual behavior
sexual maturation
stress
資料タイプ
学術雑誌論文
抄録
Purpose: Exposure to various stressors, including psychological, metabolic, and immune, in the perinatal period induces long‐lasting effects in physiological function and increase the risk of metabolic disorders in later life. In the present study, sexual maturation and sexual behavior were assessed in prenatally undernourished mature male rats.
Methods: All the pregnant rats were divided into the maternal normal nutrition (mNN) group and the maternal undernutrition (mUN) group. The mUN mothers received 50% of the amount of the daily food intake of the mNN mothers. Preputial separation and sexual behavior were observed in randomly selected pups of the mNN and mUN groups.
Results: The body weight of the mothers was significantly lighter in the mUN group than in the mNN group. Similarly, the pups in the mUN group showed a significantly lower body weight than those in the mNN group from postnatal day (PND) 1 to PND 15. The preputial separation day was significantly delayed in the mUN group, compared to the mNN group. Sexual behavior did not show any significant difference between the two groups.
Conclusion: These findings indicated that prenatal undernutrition delayed sexual maturation, but did not suppress sexual behavior, in mature male rats.
掲載誌名
Reproductive Medicine and Biology
ISSN
14470578
cat書誌ID
AA11706516
出版者
Japan Society for Reproductive Medicine|John Wiley & Sons Australia, Ltd
16
4
開始ページ
325
終了ページ
329
発行日
2017-09-16
権利情報
© 2017 The Authors. Reproductive Medicine and Biology published by John Wiley & Sons Australia, Ltd on behalf of Japan Society for Reproductive Medicine. This is an open access article under the terms of the Creative Commons Attribution License NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院