EATV and AF Prevalence
Oba, Kageyuki Tomishiro Central Hospital
Maeda, Minetaka Tomishiro Central Hospital
Maimaituxun, Gulinu Tokushima University
Yamaguchi, Satoshi Tomishiro Central Hospital
Arasaki, Osamu Tomishiro Central Hospital
Hirata, Yukina Tokushima University
Nishio, Susumu Tokushima University
Masuzaki, Hiroaki University of the Ryukyus
Epicardial adipose tissue volume
Background: Although increasing evidence suggests that epicardial adipose tissue volume (EATV) is associated with atrial fibrillation (AF), it is controversial whether there is a dose-response relationship of increasing EATV along the continuum of AF. We evaluated the effect of the EATV on the prevalence of paroxysmal AF (PAF) and persistent AF (PeAF) and the relationships with cardiac structure and functional remodeling.
Methods and Results: Subjects who underwent multidetector computed tomography (MDCT) coronary angiography because of symptoms suggestive of coronary artery disease were divided into sinus rhythm (SR) (n=112), PAF (n=133), and PeAF (n=71) groups. The EATV index (EATV/body surface area, mL/m2) was strongly associated with the prevalence of PAF and PeAF on the model adjusted for known AF risk factors. The effect of the EATV index on the prevalence of PeAF, but not on that of PAF, was modified by the left atrial (LA) dimension, suggesting that extension of the LA dimension is related to EATV expansion in PeAF. The cutoff value of the EATV index for the prevalence was higher in PeAF than in PAF (64 vs. 55 mL/m2, P<0.01).
Conclusions: The EATV index is associated with the prevalence of PAF and PeAF, and its cutoff values are predictive for PAF and PeAF development independently of other AF risk factors.
The Japanese Circulation Society
circj_82_7_1778.pdf 677 KB