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ID 113637
著者
Miyamoto, Shuji Tokushima University
Ichikawa, Ryuji Tokushima University
謝, 宜達 Tokushima University
キーワード
Biomedical imaging
Optical microscopy
Optical interferometry
資料タイプ
学術雑誌論文
抄録
Confocal laser microscopy (CLM) is a powerful tool in life science research and industrial inspection, and its image acquisition rate is boosted by scan-less imaging techniques. However, the optical-intensity-based image contrast in CLM makes it difficult to visualize transparent non-fluorescent objects or reflective objects with nanometer unevenness. In this paper, we introduce an optical frequency comb (OFC) to scan-less CLM to give the optical-phase-based image contrast. One-dimensional (1D) image pixels of a sample are separately encoded onto OFC modes via 1D spectral encoding by using OFC as an optical carrier of amplitude and phase with a vast number of discrete frequency channels. Then, line-field confocal information of amplitude and phase are decoded from a mode-resolved OFC amplitude and phase spectra obtained by dual-comb spectroscopy. The proposed confocal phase imaging will further expand the application fields of CLM.
掲載誌名
IEEE Journal of Selected Topics in Quantum Electronics
ISSN
1077260X
15584542
cat書誌ID
AA11036333
出版者
IEEE
25
1
開始ページ
6801408
発行日
2018-11-09
権利情報
© 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
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言語
eng
著者版フラグ
著者版
部局
理工学系