ID | 113813 |
著者 |
眞野, 隆充
Tokushima University
Ishikawa, Kunio
Kyushu University
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キーワード | carbonate apatite
hydroxyapatite
osteoconductivity
bone substitute
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資料タイプ |
学術雑誌論文
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抄録 | Since bone apatite is a carbonate apatite containing carbonate in an apatitic structure, carbonate content may be one of the factors governing the osteoconductivity of apatitic bone substitutes. The aim of this study was to evaluate the effects of carbonate content on the osteoconductivity of apatitic bone substitutes using three commercially available bone substitutes for the reconstruction of alveolar bone defects of a beagle mandible with simultaneous dental implant installation. NEOBONE®, Bio-Oss®, and Cytrans® that contain 0.1 mass%, 5.5 mass%, and 12.0 mass% of carbonate, respectively, were used in this study. The amount of newly formed bone in the upper portion of the alveolar bone defect of the beagle’s mandible was 0.7%, 6.6%, and 39.4% at 4 weeks after surgery and 4.7%, 39.5% and 75.2% at 12 weeks after surgery for NEOBONE®, Bio-Oss®, and Cytrans®, respectively. The results indicate that bone-to-implant contact ratio was the largest for Cytrans®. Additionally, the continuity of the alveolar ridge was restored in the case of Cytrans®, whereas the continuity of the alveolar ridge was not sufficient when using NEOBONE® and Bio-Oss®. Both Cytrans® and Bio-Oss® that has a relatively larger carbonate content in their apatitic structure was resorbed with time. We concluded that carbonate content is one of important factors governing the osteoconductivity of apatitic bone substitutes.
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掲載誌名 |
Journal of Biomedical Materials Research Part B : Applied Biomaterials
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ISSN | 15524973
15524981
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cat書誌ID | AA11881538
AA12001425
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出版者 | John Wiley & Sons
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巻 | 108
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号 | 4
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開始ページ | 1450
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終了ページ | 1459
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発行日 | 2019-10-17
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備考 | This is the peer reviewed version of the following article: Mano, T, Akita, K, Fukuda, N, et al. Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation. J Biomed Mater Res. 2020; 108: 1450– 1459, which has been published in final form at https://doi.org/10.1002/jbm.b.34492. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
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言語 |
eng
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著者版フラグ |
著者版
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部局 |
歯学系
病院
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