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ID 113960
タイトル別表記
PA Thickening on OCT in Children With CHD
著者
Homma, Yukako University of Tokushima
Ono, Akemi University of Tokushima
キーワード
Children
Congenital heart disease
Optical coherence tomography
Pulmonary arterial hypertension
資料タイプ
学術雑誌論文
抄録
Background: Pulmonary arterial (PA) wall thickening evaluated by optical coherence tomography (OCT) has been reported in adults with PA hypertension. The purpose of this study was to evaluate the feasibility of OCT for preoperative assessment of the PA wall in children with congenital heart disease (CHD).
Methods and Results: Participants comprised 39 patients with ventricular septal defect, atrial septal defect, or patent ductus arteriosus. Attempts were made to evaluate vessels of various diameters using OCT. Clearly observed vessels that were optimal for evaluation were selected and classified into 4 subgroups by diameter of the lumen. Optimal depiction was obtained in 80 of 156 vessels in total, and 25 (64.1%), 34 (87.1%), 17 (43.6%), and 4 vessels (10.3%) in each of the 1.0–<2.0 mm, 2.0–<3.0 mm, 3.0–<4.0 mm, and 4.0–5.0 mm subgroups, respectively. Arterial walls in the 2.0–<3.0 mm subgroup were the most frequently delineated, and wall thickness correlated significantly with mean PA pressure, pulmonary vascular resistance index, pulmonary-to-systemic flow ratio, and PA capacitance index (r=0.56, 0.52, 0.37, and −0.49, respectively). The 3-layered appearance was delineated in 29 of 80 vessels (36.2%). This feature had no significant correlation with pulmonary hemodynamics.
Conclusions: OCT represents a promising tool for evaluating the PA wall in children with CHD.
掲載誌名
Circulation Journal
ISSN
13469843
13474820
cat書誌ID
AA11591968
出版者
The Japanese Circulation Society
82
9
開始ページ
2350
終了ページ
2357
発行日
2018-08-24
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系