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ID 114738
タイトル別表記
降圧療法としてのニカルジピン塩酸塩を使用する脳卒中急性期患者の静脈炎発症の関連要因
Factors related to the occurrence of phlebitis in acute phase stroke patients receiving intravenous nicardipine
著者
横井, 靖子 徳島大学大学院保健科学教育部(保健学専攻) 徳島大学 教育研究者総覧
キーワード
Stroke
Nicardipine
Phlebitis
Factors
資料タイプ
学位論文
抄録
This study investigated the incidence of phlebitis associated with continuous nicardipine infusion in patients with acute-phase stroke. To identify patient factors related to the occurrence of phlebitis, and considering blood pressure values during nicardipine administration, we retrospectively investigated the nursing and medical records of 301 patients who were hospitalized for stroke. Of these, 92 patients met the inclusion criteria and had data showing whether phlebitis had occurred. We confirmed that phlebitis occurred in 38 patients (41.3%). Factors found to be significantly related to phlebitis onset were Glasgow Coma Scale (GCS)-verbal (V; p = .020) and -motor (M; p = .007), level of consciousness (total GCS score [(p = .009)]), nicardipine administration time (p = .001), nicardipine dose (p = .000), mean nicardipine rate of administration (p = .000), nicardipine dilution rate (p = .000), mean arterial blood pressure at first insertion (p = .030), and difference in the diastolic blood pressure at first insertion (p = .032). Multiple logistic regression analysis indicated that nicardipine administration time (odds ratio: 1.042, 95% confidence interval: 1.023–1.062, p = .000) was a related factor. Results also suggested that a decreased level of consciousness after the stroke onset (V3 or below and M5 or below) is related to phlebitis occurrence. Patients with stroke having a lower level of consciousness (total GCS score of 12 or below), who are being administered continuous nicardipine infusion, may require more frequent and careful infusion management and needle insertion site observation. Because phlebitis onset occurs after 24 h of continuous infusion, peripheral insertion site catheter replacement should be performed within 24 h.
掲載誌名
日本ニューロサイエンス看護学会誌
ISSN
21879354
cat書誌ID
AA12740790
出版者
Japanese Academy of Neuroscience Nursing
6
1
開始ページ
3
終了ページ
13
発行日
2019-12-31
備考
内容要旨・審査要旨・論文本文の公開
本論文は,著者Yasuko YOKOIの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3420号
学位記番号
甲保第39号
学位授与年月日
2020-03-23
学位名
博士(保健学)
学位授与機関
徳島大学
部局
医学系