ID | 114812 |
タイトル別表記 | Skeletal muscle mass and vitamin D
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著者 |
Sato, Michiko
Kenshokai Gakuen College for Health and Welfare
Morishita, Teruhiro
Kenshokai Gakuen College for Health and Welfare
Katayama, Takafumi
University of Hyogo
Satomura, Shigeko
Tokushima Prefectural Hinomine Medical Center for the Handicapped
Okuno, Hiroko
Kenshokai Gakuen College for Health and Welfare
Sumida, Nami
Kenshokai Gakuen College for Health and Welfare
Sakuma, Masae
Sugiyama Jogakuen University
Arai, Hidekazu
The University of Shizuoka
Kawaura, Akihiko
Kenshokai Gakuen College for Health and Welfare
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キーワード | Skeletal muscle mass
24-h urinary creatinine method
serum 25-hydroxyvitamin D level
walking difficulty
intestinal absorption rate
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資料タイプ |
学術雑誌論文
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抄録 | A clearer understanding of skeletal muscle mass (SMM) in middle-aged and elderly individuals is important for maintaining functionality. In the present study, age-related changes in SMM, the threshold of SMM with walking difficulty, intestinal nutrient absorption rate, and various serum factors were examined in Japanese populations of different ages. We used 24-h creatinine excretion as a measure of total body SMM. Age-related decreases in SMM, intestinal nutrient absorption rates, and serum 25-hydroxyvitamin D [25(OH)D] concentrations were significantly higher in women than in men. The cut-off values for SMM (kg), its percentage of total body weight (BW), the SMM index [SMMI] (Kg / m2), and creatinine height index (CHI) (%) in elderly individuals with walking difficulty were approximately 8-10 kg, 17-20% of BW, 3.9-4.6 kg / m2, and 44%, respectively. Serum 25(OH)D concentrations were closely associated with SMM (kg, % of BW, kg / m2) and CHI (%) as well as the intestinal absorption rates of nitrogen (%) and phosphorus (%) in women, but not in men. The present results demonstrate that vitamin D is an important metabolic factor in skeletal muscle, and contributes to the optimal management of skeletal muscle and the prevention of sarcopenia.
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掲載誌名 |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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cat書誌ID | AA12022913
AA11166929
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出版者 | Tokushima University Faculty of Medicine
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巻 | 67
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号 | 1-2
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開始ページ | 151
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終了ページ | 157
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並び順 | 151
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発行日 | 2020-02
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EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
出版社版
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部局 |
病院
医学系
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