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ID 115223
タイトル別表記
Effect of vitamin C ingestion on the vascular endothelial function exposed to transient passive smoking
抗酸化剤が受動喫煙時に動脈機能に与える影響
著者
東, 亜弥子 四国大学|徳島大学
石川, みづき 徳島大学
キーワード
passive smoking
antioxidants
vitamin C
vascular endothelial function
資料タイプ
学術雑誌論文
抄録
As well as active smoking, passive smoking is associated with a high risk of developing cardiovascular disease. The antioxidant vitamin C may inhibit the unfavorable effects of passive smoking. In this study, we investigated the effects of vitamin C ingestion on changes in the flow-mediated dilatation (FMD) at the brachial artery in patients exposed to transient passive smoking. The study participants included seven healthy adult males who were examined by high-resolution ultrasonography of the brachial artery before and after 15-minute of passive smoking. FMD was used to examine the endothelial function. Randomized crossover controlled trial, measurements were performed on two different days 120-minute after the oral administration of 1000mg of ascorbic acid (VC trial) or a placebo (P trial). Although the FMD values decreased after passive smoking in both trials, the FMD values of the VC trial were higher than those of the P trial, with significant differences between the trials observed immediately and 30-minute after passive smoking. The results of this study suggested that the ingestion of vitamin C may suppress the decrease in the vascular endothelial function caused by transient passive smoking.
掲載誌名
体力科学
ISSN
0039906X
18814751
cat書誌ID
AN00137986
出版者
日本体力医学会
68
2
開始ページ
153
終了ページ
157
発行日
2019-03-16
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
総合科学系