アクセス数 : ?
ダウンロード数 : ?
ID 111364
著者
Kannuki, Seiji the University of Tokushima
Matsumoto, Keizo the University of Tokushima
Shintani, Yasumi the University of Tokushima
板東, 浩 the University of Tokushima KAKEN研究者をさがす
Saito, Shiro the University of Tokushima
キーワード
pituitary adenoma
double pituitary adenoma
multiple endocrine neoplasia type 1
資料タイプ
学術雑誌論文
抄録
A 43-year-old male and a 39-year-old male presented with multiple pituitary adenomas with two distinct histological types. The first patient who had multiple endocrine neoplasia type 1 had developed acromegaly due to a growth hormone-releasing hormone (GHRH)-producing pancreatic tumor. Both plasma GHRH and growth hormone (GH) levels decreased to normal after resection of the pancreatic tumor. However, the plasma GH level gradually increased again and magnetic resonance imaging revealed pituitary adenoma formation. Histological examination revealed two different histological types of pituitary adenoma: GH cell adenoma and null cell adenoma. The second patient, with no such genetic condition, had a non-functioning pituitary adenoma. Histological examination revealed two different histological types of silent GH cell adenoma and silent gonadotroph adenoma. Careful histological examination is required to exclude the possibility of multiple pituitary adenomas.
掲載誌名
Neurologia Medico-Chirurgica
ISSN
04708105
13498029
cat書誌ID
AN00358613
出版者
The Japan Neurosurgical Society
36
11
開始ページ
818
終了ページ
821
発行日
1996
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系