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ID 118251
著者
Hori, Taiki Tokushima University|Anan Medical Center
山上, 紘規 Tokushima University|Anan Medical Center 徳島大学 教育研究者総覧
Yasui, Saya Anan Medical Center
Hosoki, Minae Anan Medical Center
Mitsui, Yukari Tokushima University
Masuda, Shiho Tokushima University
キーワード
Phase angle
Extracellular water-to-total body water ratio
Skeletal muscle mass index
Bioelectrical impedance analysis
Hemoglobin
Hematocrit
資料タイプ
学術雑誌論文
抄録
Background: Anemia is one of the common complications of diabetes and is associated with mortality. Phase angle (PhA), ratio of extracellular water to total body water (ECW/TBW) and skeletal muscle mass index (SMI) estimated by bioelectrical impedance analysis (BIA) have been used as prognostic indicators for various chronic diseases and frailty. We aimed to clarify the clinical significance of PhA, ECW/TBW and SMI for anemia in patients with diabetes.
Materials and methods: The values of PhA, ECW/TBW and SMI were estimated by a portable BIA device and blood samples were collected in 371 Japanese patients with diabetes. The relationships of PhA, ECW/TBW and SMI with hemoglobin (Hgb) and hematocrit (Hct) were statistically evaluated.
Results: In simple linear regression analysis, PhA and SMI were positively correlated with Hgb and Hct levels in total subjects, male subjects and female subjects. In contrast, ECW/TBW was negatively correlated with Hgb and Hct levels regardless of sex. Multivariate regression analysis showed that both PhA and ECW/TBW but not SMI independently contributed to Hgb and Hct levels after adjustment of clinical confounding factors in both males and females.
Conclusions: PhA and ECW/TBW but not SMI were associated with levels of Hgb and Hct in patients with diabetes. Therefore, aberrant values of PhA and ECW/TBW suggest a risk of anemia in diabetic patients.
掲載誌名
Heliyon
ISSN
24058440
出版者
Elsevier
9
4
開始ページ
e14724
発行日
2023-03-21
権利情報
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院
先端酵素学研究所