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ID 110871
著者
サトウ, ヒロユキ Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
内藤, 毅 Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN研究者をさがす
松下, 新悟 Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN研究者をさがす
タケバヤシ, マサル Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School
塩田, 洋 Department of Ophthalmology, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
diabetic macular edema
optical coherence tomography
sub-Tenon’s capsule injection
triamcinolone acetonide
vitrectomy
資料タイプ
学術雑誌論文
抄録
To determine whether or not a sub-Tenon’s capsule injection of triamcinolone acetonide(TA) is an effective treatment for refractory diabetic macular edema after vitrectomy. Methods : Thirty-nine eyes of 26 patients with diabetic macular edema were injected with 20 mg TA into the sub-Tenon’s capsule. The central macular thickness (CMT) measured by an optical coherence tomography (OCT) and visual acuities were compared between pre-treatment and 1, 3 months post -treatment. Results : The decrease in the mean CMT between the baseline (435 μm) and 1month (326 μm) or 3months (303 μm) time points was statistically significant. Seven eyes (70%) at 1 month and 3 months post-treatment in the vitrectomized eyes or PPV(pars plana vitrectomy)(+) group, 15 eyes(52%) at 1 month, and 19 eyes (66%) at 3 months in the non-vitrectomized eyes or PPV(-)group maintained 20% reduction in CMT from pre-treatment with a single injection of TA. The recurrence of macular edema was observed in 1 eye (14%) in the PPV(+)group, and 3 eyes (16%) in the PPV(-)group. Conclusion : The sub-Tenon’s capsule injection of TA was effective for refractory diabetic macular edema after vitrectomy. In addition, it was suggested that the treatment of vitrectomized eyes was more effective than that of non-vitrectomized eyes.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
55
3-4
開始ページ
279
終了ページ
282
並び順
279
発行日
2008-08
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
国際センター
医学系