アクセス数 : ?
ダウンロード数 : ?
ID 114702
著者
Iwasa, Masami Tokushima University
Ikegame, Akishige Tokushima University
Maruhashi, Tomoko Tokushima prefecture Naruto hospital
Sumitani, Ryohei Tokushima University
Uemura, Munenori Tokushima University
Takahashi, Mamiko Tokushima University
Oda, Asuka Tokushima University
キーワード
adenosine deaminase
multiple myeloma
pleural effusion
資料タイプ
学術雑誌論文
抄録
A 50-year-old man with immunoglobulin A type multiple myeloma (MM) was referred to our hospital after bortezomib therapy. He had high alkaline phosphatase and lactate dehydrogenase levels. Computed tomography showed osteolytic and osteoblastic bone lesions. Response to salvage chemotherapy was temporary, and he developed a right pleural effusion with high adenosine deaminase (ADA) levels. He died from bleeding associated with a pelvic bone fracture 9 months later. ADA mRNA expression and ADA secretion of the MM cells from the patient were higher than those from myeloma cell lines tested. Clinical relevance of high ADA expression in MM cells is warranted.
掲載誌名
International Journal of Myeloma
ISSN
21873143
cat書誌ID
AA12766965
出版者
Japanese Society of Myeloma
7
1
開始ページ
1
終了ページ
5
発行日
2017
EDB ID
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院