ID 110855
著者
カナモト, マミ Department of Digestive and Pediatric Surgery, nstitute of Health Biosciences The University of Tokushima Graduate School KAKEN研究者をさがす
ヨシズミ, トモハル Department of Digestive and Pediatric Surgery, nstitute of Health Biosciences The University of Tokushima Graduate School
イケガミ, トオル Department of Digestive and Pediatric Surgery, nstitute of Health Biosciences The University of Tokushima Graduate School
居村, 暁 Department of Digestive and Pediatric Surgery, nstitute of Health Biosciences The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
モリネ, ユウジ Department of Digestive and Pediatric Surgery, nstitute of Health Biosciences The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
イケモト, テツヤ Department of Digestive and Pediatric Surgery, nstitute of Health Biosciences The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
サノ, ノブヤ Department of Pathology, Institute of Health Biosciences The University of Tokushima Graduate School
島田, 光生 Department of Digestive and Pediatric Surgery, nstitute of Health Biosciences The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
a rare tumor of the liver
cholangiocellular carcinoma
cholangiolocellular carcinoma
hepatic stem cell
hepatocellular carcinoma
資料タイプ
学術雑誌論文
抄録
Cholangiolocellular carcinoma (CLC) is an extremely rare malignant liver tumor which was first defined by Steiner, et al . in 1957 (1). CLC is thought to be derived from Hering’s canal because tumor glands of CLC are morphologically similar to cholangioles. Recently, Theise, et al . reported that Hering’s canal might be composed of hepatic stem cells (3). In addition, CLC sometimes contains a hepatocellular carcinoma (HCC) or cholangiocellular carcinoma (CCC) component within the tumor. Those findings suggest that CLC might originate from hepatic stem cells. On the other hand, because of its low frequency, clinicopatholigical features of CLC have not been fully clarified yet. We herein report a case of a 71-year old man with CLC. Based on preoperative imagings, the hepatic tumor was diagnosed as HCC, and he underwent a partial hepatectomy. The tumor contained both a HCC and CCC-like area. In immunohistochemistry, cytokeratin (CK) 7, CK20, CAM5.2 was positive, and CK19 was negative, therefore the tumor was diagnosed as CLC. The diagnostic criteria have not been described clearly, so CLC is difficult to diagnose preoperatively. Further studies are needed to clarify the clinical and clinicopatholigical features of CLC.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
出版者
The University of Tokushima Faculty of Medicine
55
1-2
開始ページ
161
終了ページ
165
並び順
161
発行日
2008-02
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院
医学系