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タイトル別表記
過剰な矯正力による上顎洞への歯の移動における歯周組織形態分析
Tooth movement into the maxillary sinus
著者
前田, 有一 徳島大学大学院口腔科学教育部(口腔科学専攻)
黒田, 晋吾 The University of Tokushima KAKEN研究者をさがす
ガンゾリブ, ハリウナ The University of Tokushima
Wazen, Rima Université de Montréal
Nanci, Antonio Université de Montréal
キーワード
Experimental tooth movement
maxillary sinus
root resorption
overload
osteoblasts
Bril
資料タイプ
学位論文
抄録
Objectives: To evaluate the effect of overloading on the palatal movement of the maxillary molar.
Materials and methods: The maxillary first molar of male C57Bl/6 mice was moved palatally with 10-g or 30-g load for 14 days, and amount of tooth movement was longitudinally measured on micro-computed tomography images (each group, N=5). Bone remodeling around the molar root under the 30-g load was evaluated at days 3, 5, 7, and 14 after the starting of tooth movement using histomorphometry and immunodetection of bone-restricted Ifitm (interferon inducible transmembrane)-like protein, a novel marker of active bone formation (each group, N=5).
Result: In the 10-g load group, the amount of tooth movement increased dramatically between day 5 to day 7, and gradually increased thereafter. In 30-g load group, tooth movement at day 5 and day 7 was significantly lower than those in the 10-g load group; however, total tooth movement for 14 days was similar in both groups. Orthodontic load of 30-g stimulated bone formation on the sinus wall, but bone resorption on the periodontal ligament side was delayed because of the hyalinization, which means strong force application was not accelerate tooth movement. Moreover, some root resorption was induced under the excessive force application.
Conclusion: Root penetration into sinus and bone height reduction does not occur because new bone formation on the maxillary sinus is induced prior to bone resorption on the periodontal side, even though excessive orthodontic force is applied. However, excessive force is subject to induce root resorption.
掲載誌名
American Journal of Orthodontics and Dentofacial Orthopedics
ISSN
08895406
cat書誌ID
AA10705697
AA11537430
出版者
The American Association of Orthodontists|Elsevier
148
3
開始ページ
423
終了ページ
430
発行日
2015-08-28
備考
内容要旨・審査要旨・論文本文の公開:
内容要旨 : LID201507301004.pdf
審査要旨 : LID201507301005.pdf
論文本文 : k2861_fulltext.pdf
著者の申請により要約(2015-09-18公開)に替えて論文全文を公開(2019-06-06)
本論文は, 著者Yuichi Maedaの学位論文として提出され, 学位審査・授与の対象となっている。
権利情報
© 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0
license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第2861号
学位記番号
甲口第400号
学位授与年月日
2015-07-16
学位名
博士(歯学)
学位授与機関
徳島大学
部局
歯学系