| ID | 118012 |
| 著者 |
Yagi, Mai
Tokushima University|Tokushima Prefectural Central Hospital
Muraki, Sho
Tokushima University|Shikoku Medical Center for Children and Adults
Fujimoto, Shota
Tokushima University
|
| キーワード | gastric cancer
pulmonary tumor thrombotic microangiopathy (PTTM)
cardiac catheterization
vascular endothelial growth factor (VEGF)
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| 資料タイプ |
学術雑誌論文
|
| 抄録 | A 66-year-old Japanese man receiving systemic chemotherapy for advanced gastric cancer presented with exertional dyspnea. D-dimer was elevated in the blood. Echocardiography revealed pulmonary hypertension, and a ventilation-perfusion scan indicated decreased perfusion in the bilateral lungs. Cardiac catheterization showed no evidence of pulmonary artery embolization and revealed cytologically confirmed adenocarcinoma. Thus, pulmonary tumor thrombotic microangiopathy (PTTM) was diagnosed. The patient died of respiratory failure on the 17th hospitalization day despite systemic chemotherapy. Retrospective serological testing revealed increased vascular endothelial growth factor in the pulmonary artery blood. This is a rare case with antemortem cytologically proven PTTM mediated by VEGF.
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| 掲載誌名 |
Internal Medicine
|
| ISSN | 13497235
|
| 出版者 | The Japanese Society of Internal Medicine
|
| 巻 | 61
|
| 号 | 10
|
| 開始ページ | 1491
|
| 終了ページ | 1495
|
| 発行日 | 2022-05-15
|
| 権利情報 | The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
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| 言語 |
eng
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| 著者版フラグ |
出版社版
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| 部局 |
病院
医学系
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