直近一年間の累計
アクセス数 : ?
ダウンロード数 : ?
ID 111174
著者
Inoue, Miki Tokushima Prefectural Central Hospital
Ono, Akemi Tokushima Prefectural Central Hospital
Terada, Tomomasa Tokushima Prefectural Central Hospital
Kawahito, Masami Tokushima Prefectural Central Hospital
Mori, Kazuhiro Tokushima Prefectural Central Hospital
キーワード
Kawasaki disease
myocarditis
encephalopathy
steroid
資料タイプ
学術雑誌論文
抄録
Severe-type Kawasaki disease (KD) complicated by serious myocarditis and encephalopathy can be successfully treated without abnormality of the coronary arteries by steroid pulse treatment and intravenous immunoglobulin (IVIg). A 4-year-old Japanese girl was diagnosed with KD due to a 6-day history of fever, rash, flushed lips, conjunctival hyperemia, palmar edema, and cervical lymphadenopathy. The day after initiation of IVIg and aspirin, cardiac gallop rhythm was identified. Cardiac ultrasonography revealed severe left ventricular dysfunction. Disturbance of consciousness, hallucinations, and slurred speech were also observed. Magnetic resonance imaging showed no abnormalities, but electroencephalography revealed high-voltage slow waves. Despite this serious disease, cardiac function and neurological abnormalities showed complete recovery without dilatation of the coronary arteries by steroid pulse treatment and additional IVIg. Follow-up at 15 months revealed no abnormality of the coronary arteries. In conclusion, we suggest that early combined treatment with steroid and IVIg is effective for serious KD complicated by myocarditis and encephalopathy.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
63
1-2
開始ページ
140
終了ページ
143
並び順
140
発行日
2016-02
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院