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ID 114525
タイトル別表記
統合失調症患者の社会機能と認知機能の関連
Social and cognitive functions in schizophrenia
著者
武田, 知也 Tokushima University
Tanaka, Tsunehiko Niigata University
兼田, 康宏 Iwaki Clinic
キーワード
schizophrenia
social function
negative symptom
cognitive function
speed of processing
資料タイプ
学位論文
抄録
Purpose: The purpose of the present study was to examine clinical factors related to social function in people with schizophrenia.
Patients and methods: The participants were 55 stabilized outpatients with schizophrenia. Their mean age was 39.36 (SD =10.65) years. Social function was assessed using the Quality of Life Scale (QLS). Cognitive function was evaluated with the Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB). Clinical symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS), the Calgary Depression Scale for Schizophrenia, and the Drug-Induced Extrapyramidal Symptoms Scale.
Results: Neither the MCCB cognitive domain score nor composite score was correlated with the QLS scores. However, of the 10 MCCB subtests, the Trail Making Test Part A and the Brief Assessment of Cognition in Schizophrenia-Symbol Coding (BACS-SC) scores were positively correlated with the QLS scores. Among clinical variables, especially the PANSS negative syndrome scale score had a strong negative correlation with the QLS scores. Stepwise regression analyses showed that the PANSS negative syndrome scale score was an independent predictor of the QLS scores, and although the BACS-SC score predicted the QLS common objects and activities subscale score, the association was not so strong compared to the PANSS negative syndrome scale score.
Conclusion: These results indicate that speed of processing evaluated by BACS-SC could predict some aspect of social function but negative symptoms have a much stronger impact on global social function in people with schizophrenia.
掲載誌名
Neuropsychiatric Disease and Treatment
ISSN
11766328
出版者
Dove Medical Press
14
開始ページ
2215
終了ページ
2224
発行日
2018-08-30
備考
内容要旨・審査要旨・論文本文の公開
本論文は,著者Takeo Tominagaの学位論文として提出され,学位審査・授与の対象となっている
権利情報
© 2018 Tominaga et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
乙第2111号
学位記番号
乙医第1759号
学位授与年月日
2020-03-05
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系
総合科学系
病院
保健管理・総合相談センター
特別修学支援室