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ID 113405
タイトル別表記
CRP in PMR and RS3PE syndrome
著者
田畑, 良 The University of Tokushima KAKEN研究者をさがす
湯浅, 志乃 Tokushima Prefectural Central Hospital
中西, 嘉憲 The University of Tokushima
Kawahito, Keisuke Yoshinogawa Medical Center
稲葉, 圭佑 The University of Tokushima
稲葉, 香織 The University of Tokushima
近藤, 啓介 Ehime Prefectural Central Hospital 徳島大学 教育研究者総覧
Umetani, Kazumasa Tokyo Bei Urayasu Ichikawa Medical Center
Miyatake, Akiko Naruto Yamakami Hospital
キーワード
PMR
RS3PE syndrome
C-reactive protein
prednisolone
relapse
資料タイプ
学術雑誌論文
抄録
Polymyalgia rheumatica (PMR) and remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome are common inflammatory rheumatic diseases in the elderly. In this study, we investigate predictive factors which correspond to subsequent disease control of PMR and RS3PE syndrome. Twenty four patients, which contained 18 PMR and 6 RS3PE syndrome, were treated with initial dosages of 10-20 mg per day oral prednisolone, and the dosage of prednisolone was then tapered. Significantly higher initial CRP was observed in patients with poor disease control than in those with good disease control afterwards. The number of patients with negative CRP after 4 weeks was significantly more in patients with good disease control after 1 year than in those with poor disease control. Patients were shown to be in good disease control status after 1 year when CRP after 4 weeks became negative even if they had initial high CRP. Our study clarify that to make CRP negative after 4 weeks is associated with subsequent suppression of the disease activity and with decreased dosages of corticosteroids.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA12022913
AA11166929
出版者
Tokushima University Faculty of Medicine
66
1-2
開始ページ
112
終了ページ
118
並び順
112
発行日
2019-02
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院
医学系