ID | 109636 |
タイトルヨミ | ニンシン オ ケイキ ニ ジョウミャク ケッセンショウ オ ハッショウシ センテンセイ アンチトロンビンIII ケッソンショウ ト シンダン サレタ イチレイ
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タイトル別表記 | A case of venous thrombosis due to congenital antithrombin III deficiency triggered by pregnancy
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著者 |
髙木, 恵理
徳島大学病院循環器内科
太田, 理絵
徳島大学病院循環器内科
仁木, 敏之
徳島大学病院循環器内科
高島, 啓
徳島大学病院循環器内科
坂東, 左知子
徳島大学病院循環器内科
發知, 淳子
徳島大学病院循環器内科
上田, 由佳
徳島大学病院循環器内科
冨田, 紀子
徳島大学病院循環器内科
中山, 聡一郎
徳島大学病院産科婦人科
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キーワード | antithrombin III deficiency
thrombophilia
venous thrombosis
pregnancy
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資料タイプ |
学術雑誌論文
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抄録 | Congenital antithrombin III (AT III) deficiency is an inherited autosomal dominant disorder. Patients often suffer from recurrent venous thromboses that are triggered by several occasions (operation, gestation, trauma, oral contraceptive drug etc.). Moreover, 60% of them are said to be associated with pulmonary embolism.
The patient of this report is 27-year-old pregnant woman in the first trimester. She felt pain in the back of her head and left auricle and presented with dyslexia and aphasia in late of March, 20XX. Getting CT brain scan, MRI brain scan, and blood sampling at the nearby hospital, she was suspected of having thrombosis of left sigmoid and transverse sinus due to AT III deficiency. Because she wanted to give birth to her first child without termination, she was referred to our hospital. We used heparin as the anticoagulant therapy because warfarin had the risk of teratogenesis. But in condition of low serum level of AT III activity, it didn’t work effectively. So we also did frequent complement of AT III. Strict anticoagulant therapy resulted in better outcome for both the patient and her baby without fatal venous thromboses or fetal complications. |
掲載誌名 |
四国医学雑誌
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ISSN | 00373699
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cat書誌ID | AN00102041
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出版者 | 徳島医学会
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巻 | 69
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号 | 3-4
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開始ページ | 179
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終了ページ | 186
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並び順 | 179
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発行日 | 2013-08-25
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備考 | 著者英表記誤表記あり(誤)Kazutoshi Maeda→(正)Kazuhisa Maeda
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フルテキストファイル | |
言語 |
jpn
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著者版フラグ |
出版社版
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部局 |
病院
医学系
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