ID 83836
著者
後東, 久嗣 Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
埴淵, 昌毅 Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN研究者をさがす
坂口, 暁 Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School
カネマツ, タカノリ Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School
柿内, 聡司 Department of Medical Oncology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN研究者をさがす
富本, 英樹 Department of Medical Oncology, Institute of Health Biosciences, the University of Tokushima Graduate School
吾妻, 雅彦 Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
手塚, 敏史 Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN研究者をさがす
タダ, ヒロヤ Department of Medical Oncology, Institute of Health Biosciences, the University of Tokushima Graduate School
ミキ, ユキヨ Outpatient Chemotherapy Unit, Tokushima University Hospital
ナカムラ, トシミ Outpatient Chemotherapy Unit, Tokushima University Hospital
曽根, 三郎 Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School|Department of Medical Oncology, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
西岡, 安彦 Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
outpatient chemotherapy
lung cancer
best overall response
time to treatment failure
資料タイプ
学術雑誌論文
抄録
Platinum-doublet regimens and docetaxel as first- and second-line chemotherapy,
respectively, are shown to prolong the survival of lung cancer patients in various
randomized phase III studies. However, the evidence for the efficacy of chemotherapy
for lung cancer in the clinical practice is still insufficient. In the present study, we
investigated the effectiveness and safety of outpatient chemotherapy for lung cancer in
the clinical practice. Ninety-four lung cancer cases were retrospectively analyzed. Among
these cases, 67 (71.3%) were non-small cell lung cancer (NSCLC) and 27 (28.7%) were
small cell lung cancer (SCLC). The response rates in SCLC and NSCLC patients were
55.6% (15/27) and 16.9% (11/65), respectively. Objective tumor response rates for the patients
were found to decrease substantially with each line of treatment as described previously.
All adverse events were well tolerated and no treatment-related death was observed.
Median time to treatment failures (TTFs) of first-line treatment were 10.1 months
and 4.8 months in SCLC and NSCLC, respectively. These findings indicate that even in
the setting of clinical practice, the efficacy and safety of chemotherapy is strictly insured
by the appropriate therapeutic management.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
58
3-4
開始ページ
219
終了ページ
226
並び順
219
発行日
2011-08
備考
The journal of medical investigation : http://medical.med.tokushima-u.ac.jp/jmi/index.html
EDB ID
フルテキストファイル
言語
eng
部局
医学系
病院