ID 113070
著者
資料タイプ
学術雑誌論文
抄録
A variety of biological redox reactions are mediated by flavoenzymes due to the unique redox activity of isoalloxazine ring systems, which are found in flavin cofactors. In the field of synthetic organic chemistry, the term “flavin” is generally used for not only isoalloxazines but also related molecules including their isomers and some analogues, and those having catalytic activity are called flavin catalyst. Flavin catalysts are typically metal-free, and their catalytic activity can be readily accessed using mild terminal oxidants such as H2O2 and O2; therefore, redox reactions with these compounds have great promise as alternatives to reactions with conventional metal catalysts for the sustainable production of important chemicals. We recently became interested in using polymers for the development of flavin catalysts, especially to improve their practicality and advance the field of catalysis. Here, we summarize our recent research on such flavin-polymer collaborations including the development of facile preparation methods for flavin catalysts using polymers, readily reusable polymer-supported flavin catalysts, and flavin-peptide-polymer hybrids that can catalyze the first flavoenzyme-mimetic aerobic oxygenation reactions.
掲載誌名
Polymer Journal
ISSN
00323896
13490540
cat書誌ID
AA00777013
出版者
The Society of Polymer Science, Japan|Springer Nature
50
開始ページ
941
終了ページ
949
発行日
2018-07-10
備考
This is the Author's Accepted Manuscript of the following article: Advanced flavin catalysts elaborated with polymers, Yukihiro Arakawa, Keiji Minagawa & Yasushi Imada, Polymer Journal 50, 941-949 (2018), which has been published in final form at https://doi.org/10.1038/s41428-018-0089-8.
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
著者版
部局
理工学系
教養教育院