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ID 116179
著者
Nakamura, Tenta Tokushima University
Ara, Tabassum Tokushima University
Oda, Asuka Tokushima University
Sato, Hideo Tokushima University
キーワード
Antioxidant
Biaryl dimer
Natural product
Dihydroisocoumarin
資料タイプ
学術雑誌論文
抄録
A biaryl dimer based on eurotiumide A, a dihydroisocoumarin-type natural product possessing a 1,4-hydroquinone skeleton, was synthesized herein. The radical scavenging activity and cytotoxicity were evaluated. The prepared biaryl dimer and eurotiumide A displayed comparable potent antioxidant activities to those of α-tocopherol and edaravone. However, the biaryl dimer did not show any cytotoxicity against murine colon and human myeloma cells.
掲載誌名
Tetrahedron Letters
ISSN
00404039
cat書誌ID
AA00861801
AA11539822
出版者
Elsevier
74
開始ページ
153176
発行日
2021-05-10
備考
論文本文は2023-05-10以降公開予定
権利情報
© 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
EDB ID
出版社版DOI
出版社版URL
言語
eng
著者版フラグ
その他
部局
薬学系
病院
医学系