ID 113353
タイトル別表記
日本人における母体血及び臍帯血血中25(OH)D濃度の季節変動
Vitamin D during pregnancy in Japanese
著者
祖川, 英至 徳島大学大学院医科学教育部(医学専攻)
Yoshida, Atsuko Tokushima University
前田, 和寿 Tokushima University|Shikoku Medical Center for Children and Adults KAKEN研究者をさがす
キーワード
25-hydroxyvitamin D
pregnancy
cord blood
season
vitamin D
資料タイプ
学位論文
抄録
We aimed to demonstrate that the serum 25-hydroxyvitamin D (25(OH)D) level in maternal and umbilical cord blood has a seasonal variation in Japanese women. The study cohort comprised 256 healthy Japanese women with a singleton pregnancy who delivered after 36 gestational weeks between 2012 and 2015. The season at delivery was categorized for 3 months and recorded as “spring”, “summer”, “autumn” and “winter”. Subjects were divided into four groups according to season. A sample of peripheral venous blood at 35-36 gestational weeks and blood from the umbilical vein at delivery were taken. The mean serum 25(OH)D concentration (ng/mL) in maternal blood for each season (spring, summer, autumn and winter) was 18.0 (±6.7), 17.1 (±5.1), 21.6 (±8.0) and 16.0 (±5.1), whereas that for umbilical cord blood was 8.8 (±3.6), 8.6 (±2.6), 10.7 (±3.5) and 8.6 (±2.1), respectively. The mean serum 25(OH)D concentration of maternal and umbilical cord blood in autumn was higher than that for the other three seasons. In pregnant Japanese women, the mean serum 25(OH)D concentration in maternal and umbilical cord blood was affected by the season of delivery, with both being highest in autumn. Regardless of the season, the maternal serum concentration of 25(OH)D was low in Japan.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA12022913
AA11166929
出版者
Tokushima University Faculty of Medicine
66
1-2
開始ページ
128
終了ページ
133
並び順
128
発行日
2019-02
備考
内容要旨・審査要旨・論文本文の公開
本論文は,著者Eishi Sogawaの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3258号
学位記番号
甲医第1407号
学位授与年月日
2019-03-22
学位名
博士(医学)
学位授与機関
徳島大学
部局
病院
医学系