ID | 111120 |
著者 |
Matsuura, Sayaka
Tokushima University
Shirai, Yumiko
Iga City General Hospital
Kubo, Miyu
Tokushima University
Nayama, Chisako
Tokushima University
Okitsu, Masami
Tokushima University
Oiwa, Yuu
Tokushima University
鈴木, 佳子
Tokushima University
Murata, Tomohiro
Mie University|Iga City General Hospital
Ishikawa, Eiji
Mie University|Iga City General Hospital
Miki, Chikao
Iga City General Hospital
|
キーワード | bioelectrical impedance analysis
nutrition
prealbumin
protein-energy wasting
|
資料タイプ |
学術雑誌論文
|
抄録 | Serum transthyretin (TTR), also known as prealbumin, is a reliable nutritional indicator and an independent prognostic factor for maintenance hemodialysis patients. However, we recently reported that serum TTR levels did not affect protein−energy wasting (PEW). In this study, we investigated factors affecting serum TTR levels in 60 maintenance hemodialysis patients. The patients were divided into High-TTR and Low-TTR groups according to the median serum TTR level. Albumin levels were significantly higher and C-reactive protein (CRP) levels were significantly lower in the High-TTR group than in the Low-TTR group. Although body fat mass was significantly higher in the High-TTR group than in the Low-TTR group, no significant difference in body fat ratio were observed. These findings suggest that body fat mass is related to serum TTR levels, apart from factors such as albumin and CRP levels, which showed correlations with serum TTR levels. Because body fat mass is related to better survival in maintenance hemodialysis patients, it may contribute to the prognostic value of serum TTR levels. In addition, in such patients, it may be important to evaluate body fatmass rather than body fat ratio and to maintain the minimum necessary body fat mass.
|
掲載誌名 |
The Journal of Medical Investigation
|
ISSN | 13496867
13431420
|
cat書誌ID | AA11166929
AA12022913
|
出版者 | Faculty of Medicine Tokushima University
|
巻 | 64
|
号 | 3-4
|
開始ページ | 222
|
終了ページ | 227
|
並び順 | 222
|
発行日 | 2017-08
|
EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
|
著者版フラグ |
出版社版
|
部局 |
医学系
|