ID | 113967 |
著者 |
井戸, 佑介
University of Tokushima
Yoshitomi, Tatsuki
University of Tokushima
大倉, 一人
Suzuka University of Medical Science
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キーワード | Voltage-dependent anion channel (VDAC)
Mitochondria
Pseudogene
Synteny
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資料タイプ |
学術雑誌論文
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抄録 | Rodent and human genomes were screened to identify pseudogenes of the type 1 voltage-dependent anion channel (VDAC1) in mitochondria. In addition to the 16 pseudogenes of rat VDAC1 identified in our recent study, 15 and 13 sequences were identified as pseudogenes of VDAC1 in mouse and human genome, respectively; and 4, 2, and 1 sequences, showing lower similarities with the VDAC1 sequence, were identified as “possible pseudogene candidates” in rat, mouse, and human, respectively. No syntenic combination was observed between rodent and human pseudogenes, but 2 and 1 possible pseudogene candidates of VDAC1 of rat and mouse, respectively, were found to have syntenic counterparts in mouse and rat genome, respectively; and these syntenic counterparts were genuine VDAC1 pseudogenes. Therefore, syntenic combinations of pseudogenes of VDAC1 were useful not only for a better understanding of the phylogenetic divergence history of rodents but also for ascertaining possible pseudogene candidates as genuine pseudogenes.
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掲載誌名 |
Genomics
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ISSN | 08887543
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cat書誌ID | AA10678346
AA11537587
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出版者 | Elsevier
|
巻 | 104
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号 | 2
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開始ページ | 128
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終了ページ | 133
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発行日 | 2014-05-22
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権利情報 | Open Archive
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EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
出版社版
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部局 |
先端酵素学研究所
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