ID 82891
著者
髙田, 信二郎 Division of Rehabilitation, Tokushima University Hospital
米津, 浩 Department of Orthopedic Surgery, Mitoyo General Hospital
シバタ, アキラ Faculty of Pharmaceutical Science, Yasuda Women’s University, Hiroshima
江西, 哲也 Division of Rehabilitation, Tokushima University Hospital KAKEN研究者をさがす
佐藤, 紀 Division of Rehabilitation, Tokushima University Hospital 徳島大学 教育研究者総覧 KAKEN研究者をさがす
高橋, 光彦 Department of Orthopedics, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN研究者をさがす
中尾, 成孝 Division of Rehabilitation, Tokushima University Hospital
小松, 宏慈 Division of Rehabilitation, Tokushima University Hospital
安井, 夏生 Division of Rehabilitation, Tokushima University Hospital|Department of Orthopedics, Institute of Health Biosciences, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
Fourier transform infrared spectroscopy
bone quality
peripheral quantitative computed tomography
three-point bending test
資料タイプ
学術雑誌論文
抄録
We studied the changes of biomaterial and biomechanical properties of the rat
femur during development. Thirty male Wistar rats were allocated to 6 groups : aged 6
weeks (n=5), 9 weeks (n=5), 12 weeks (n=5), 15 weeks (n=5), 24 weeks (n=5), and 36 weeks
(n=5). The mineral to matrix ratio (M/M ratio) of rat femur by Fourier transform infrared
spectroscopy was 0.97 0.10 at the age of 6 weeks, and reached the maximum of 1.52
0.17 at the age of 36 weeks. Total bone mineral density (BMD) by peripheral quantitative
computed tomography of the femoral shaft aged 6 weeks was 479.1 58.7 mg/cm3, and
reached the maximum of 1022.2 42.3 mg/cm3 at the age of 36 weeks. The ultimate load to
failure of the femur of the rat aged 6 weeks by the three-point bending test was 29.6 6.1 N.
At the age of 36 weeks, the ultimate load to failure of the rat femur increased to the maximum
of 283.5 14.7 N. The results showed that the M/M ratio increased with development
as total BMD and bone strength increased. The results suggest that the M/M ratio is one
of the determinants of the biomaterial and biomechanical properties of bone.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
58
3-4
開始ページ
197
終了ページ
202
並び順
197
発行日
2011-08
備考
The journal of medical investigation : http://medical.med.tokushima-u.ac.jp/jmi/index.html
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
部局
病院
医学系