直近一年間の累計
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ID 114301
タイトル別表記
Left Side Electrode of DBS Caused an Acute Mood Swing
著者
キーワード
Subthalamic nucleus deep brain stimulation
Parkinson’s disease
Manic episode
Depressive episode
Lateral balance
資料タイプ
学術雑誌論文
抄録
No previous reports have described a case in which deep brain stimulation elicited an acute mood swing from a depressive to manic state simply by switching one side of the bilateral deep brain stimulation electrode on and off. The patient was a 68-year-old woman with a 10-year history of Parkinson’s disease. She underwent bilateral subthalamic deep brain stimulation surgery. After undergoing surgery, the patient exhibited hyperthymia. She was scheduled for admission. On the first day of admission, it was clear that resting tremors in the right limbs had relapsed and her hyperthymia had reverted to depression. It was discovered that the left-side electrode of the deep brain stimulation device was found to be accidentally turned off. As soon as the electrode was turned on, motor impairment improved and her mood switched from depression to mania. The authors speculate that the lateral balance of stimulation plays an important role in mood regulation. The current report provides an intriguing insight into possible mechanisms of mood swing in mood disorders.
掲載誌名
Clinical Psychopharmacology and Neuroscience
ISSN
17381088
20934327
cat書誌ID
AA12041419
出版者
The Korean College of Neuropsychopharmacology
16
4
開始ページ
494
終了ページ
496
発行日
2018-11-30
権利情報
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
病院
医学系
特別修学支援室