ID 110743
著者
テラザワ, トシヒデ Department of Digestive and Pediatric Surgery, The University of Tokushima School of Medicine
ミヤケ, ヒデノリ Department of Digestive and Pediatric Surgery, The University of Tokushima School of Medicine
クラハシ, ミホ Department of Digestive and Pediatric Surgery, The University of Tokushima School of Medicine
田代, 征記 Department of Digestive and Pediatric Surgery, The University of Tokushima School of Medicine 徳島大学 教育研究者総覧
キーワード
gallbladder
lymphatic drainage
gallbladder carcinoma
heptic invasion
pig
資料タイプ
学術雑誌論文
抄録
In the special occasion that the physiological lymphatic flow is obstructed, gallbladder carcinoma (GBC)may spread into the liver via lymphatic route. Therefore, this study was conducted to find out the direct lymphatic route draining into the liver from the gallbladder using pigs with ligated cystic ducts. After injecting the carbon particle suspension (CH40) or the contrast medium (Lipiodol) into the subserosal layer of the gallbladder, the lymphatic route into the liver was examined both macroscopically and histologically. In controls, CH40 or Lipiodol drained along the cystic duct toward the hepatoduodenal ligament. After occlusion of cystic duct, CH40 was interrupted at the ligated point, and then spread into the liver nearby the gallbladder bed, running off to the liver hilus, toward the hepatoduodenal ligament. This route was confirmed by the Lipiodol drainage into the right median lobe of the liver, equivalent to the segments Vand IV a in humans. We presented for the first time the emergence of lymphatic drainage from the gallbladder into the liver after the occlusion of physiological lymphatic route using pigs. This implies that the direct spread into the segments Vand IVa of liver should be considered in the surgical treatment of advanced GBC.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
51
3-4
開始ページ
210
終了ページ
217
並び順
210
発行日
2004-08
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系