ID | 118536 |
タイトル別表記 | Sudden death after COVID-19 vaccination
|
著者 |
Kurata, Hiromitsu
Tokushima University|Nakazu-Yagi Hospital
Umemoto, Hitomi
Tokushima University
Iseki, Hirofumi
Tokushima University|Nakazu-Yagi Hospital
|
キーワード | Systemic inflammation
Myopericarditis
COVID-19
Vaccines
Sudden death
Autopsy
|
資料タイプ |
学術雑誌論文
|
抄録 | A 14-year-old Japanese girl died unexpectedly 2 days after receiving the third dose of the BNT1262b2 mRNA COVID-19 vaccine. Autopsy findings showed congestive edema of the lungs, T-cell lymphocytic and macrophage infiltration in the lungs, pericardium, and myocardium of the left atria and left ventricle, liver, kidneys, stomach, duodenum, bladder, and diaphragm. Since there was no preceding infection, allergy, or drug toxicity exposure, the patient was diagnosed with post-vaccination pneumonia, myopericarditis, hepatitis, nephritis, gastroenteritis, cystitis, and myositis. Although neither type of inflammation is fatal by itself, arrhythmia is reported to be the most common cause of death in patients with atrial myopericarditis. In the present case, arrhythmia of atrial origin was assumed as the cause of cardiac failure and death. In sudden post-vaccination deaths, aggressive autopsy systemic search and histological examination involving extensive sectioning of the heart, including the atrium, are indispensable.
|
掲載誌名 |
Legal Medicine
|
ISSN | 18734162
13446223
|
cat書誌ID | AA11327981
AA11644485
|
出版者 | Elsevier
|
巻 | 63
|
開始ページ | 102244
|
発行日 | 2023-03-20
|
権利情報 | © 2023. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
|
著者版フラグ |
著者版
|
部局 |
医学系
|