アクセス数 : ?
ダウンロード数 : ?
ID 115595
タイトル別表記
Erosive Esophagitis in Women With Metabolic Syndrome
著者
曽我部, 正弘 The University of Tokushima|Kagawa Prefectural Cancer Detection Center 徳島大学 教育研究者総覧 KAKEN研究者をさがす
Yamanoi, Akira Kagawa Prefectural Cancer Detection Center
資料タイプ
学術雑誌論文
抄録
Obesity and metabolic syndrome (MS) are strongly associated with erosive esophagitis (EE). The prevalence of MS and EE, and the distribution of adipose tissue have been known to differ markedly between men and women. Although the prevalence of EE in men with MS is known to be higher in visceral fat type MS (V-type MS) than in subcutaneous fat type MS (S-type MS), the association between EE and the types of MS in women with MS is unclear. This study was a cross-sectional study elucidating the association between EE and the types of MS in women with MS.
Subjects were 454 women with MS who underwent a regular health check-up. A distinction was made between V-type MS and S-type MS and the prevalence of EE and the association between EE and other data were elucidated.
Although there were some significant different factors in characteristics between V-type MS and S-type MS, there was no significant difference in the prevalence of EE between V-type MS and S-type MS. The presence of Helicobacter pylori (H. pylori) was significantly lower than in subjects with EE (13.7%) than in subjects without EE (41.9%). The frequency of hiatal hernia was significantly higher in subjects with EE (60.8%) than in subjects without EE (24.6%). Logistic regression analysis showed hiatal hernia (odds ratio: 4.673; 95% confidence interval: 2.448–8.920; P < 0.001), hemoglobin A1c (HbA1c) (2.325; 1.110–4.870; P < 0.05), and the presence of H. pylori (0.239; 0.101–0.567; P < 0.005) were significant predictors of the prevalence of EE.
V-type MS may not be such an important factor for the prevalence of EE in women with MS as in men with MS. The absence of H. pylori, hiatal hernia, and HbA1c may be more important for the prevalence of EE than the types of MS in women with MS.
掲載誌名
Medicine
ISSN
00257974
15365964
cat書誌ID
AA00728867
出版者
Wolters Kluwer Health
93
28
開始ページ
e276
発行日
2014-12
権利情報
This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0(https://creativecommons.org/licenses/by-nc-nd/4.0/), where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially.
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系