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ID 111150
タイトル別表記
関節リウマチ患者における前足部の切除関節形成術後の足部機能、疾患活動性および能力低下の変化
Changes after forefoot surgery in RA
著者
澤近, 房和 徳島大学大学院医科学教育部(医学専攻)
上村, 浩一 The University of Tokushima KAKEN研究者をさがす
山口, 美輪 The University of Tokushima KAKEN研究者をさがす
Bahari, Tirani The University of Tokushima
Miki, Keisuke The University of Tokushima
Todo, Satoshi Utazu Hospital
Inoo, Masayuki Utazu Hospital
Onishi, Ikuko Utazu Hospital
Kurata, Noriyuki Utazu Hospital
キーワード
rheumatoid arthritis
resection arthroplasty of the forefoot
foot function
資料タイプ
学位論文
抄録
The purpose of this study was to investigate the changes in foot function, disease activity, and disability in patients with RA after resection arthroplasty of the forefoot (arthroplasty). Arthroplasty was performed on 11 patients with RA. All study patients underwent clinical assessment to measure disease activity (Disease Activity Score in 28 Joints-C-reactive protein, DAS28-CRP), disability (Health Assessment Questionnaire- Disability Index, HAQ-DI) and foot function (Foot Function Index, FFI) at the following stages : preoperatively and 1, 3, and 12 months after surgery. Following arthroplasty, foot function improved significantly, as assessed by FFI total and subscales (pain, disability, and limitation of activity) (P<0.001, P <0.001, P<0.001, and P=0.002, respectively). Disease activity was significantly improved in relation to DAS28-CRP and its subscales of number of swollen joints and patient global assessment (PtGA) (P=0.033, P=0.008, and P=0.038, respectively). There was no significant difference in disability, as assessed by the HAQ-DI and its subscale, HAQ-walking (P=0.150 and P=0.597, respectively). Foot function improved significantly after arthroplasty, and was maintained at 12 months postoperatively. Additionally, our study showed that disease activity and its subscale PtGA improved after arthroplasty.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
63
1-2
開始ページ
38
終了ページ
44
並び順
38
発行日
2016-02
備考
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201512161004.pdf
論文本文 : LID201603171005.pdf
本論文は,著者Fusakazu Sawachikaの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第2890号
学位記番号
甲医第1265号
学位授与年月日
2015-11-26
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系