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ID 111444
タイトル別表記
Arterial spin labeling灌流画像で得られる血管内高信号は内頚動脈の閉塞部位を予測する
著者
曽我部, 周 徳島大学大学院医科学教育部(医学専攻) 徳島大学 教育研究者総覧
Yoshioka, Shotaro Tokushima University
Kitazato, Keiko T. Tokushima University
キーワード
Magnetic resonance imaging
Arterial spin labeling
Internal carotid artery occlusion
Occluded segment
資料タイプ
学位論文
抄録
Introduction
Arterial spin labeling (ASL) involves perfusion imaging using the inverted magnetization of arterial water. If the arterial arrival times are longer than the post-labeling delay, labeled spins are visible on ASL images as bright, high intra-arterial signals (IASs); such signals were found within occluded vessels of patients with acute ischemic stroke. The identification of the occluded segment in the internal carotid artery (ICA) is crucial for endovascular treatment. We tested our hypothesis that high IASs on ASL images can predict the occluded segment.
Methods
Our study included 13 patients with acute ICA occlusion who had undergone angiographic and ASL studies within 48 h of onset. We retrospectively identified the high IAS on ASL images and angiograms and recorded the occluded segment and the number of high IAS-positive slices on ASL images. The ICA segments were classified as cervical (C1), petrous (C2), cavernous (C3), and supraclinoid (C4).
Results
Of seven patients with intracranial ICA occlusion, five demonstrated high IASs at C1–C2, suggesting that high IASs could identify stagnant flow proximal to the occluded segment. Among six patients with extracranial ICA occlusion, five presented with high IASs at C3–C4, suggesting that signals could identify the collateral flow via the ophthalmic artery. None had high IASs at C1–C2. The mean number of high IAS-positive slices was significantly higher in patients with intra- than extracranial ICA occlusion.
Conclusion
High IASs on ASL images can identify slow stagnant and collateral flow through the ophthalmic artery in patients with acute ICA occlusion and help to predict the occlusion site.
掲載誌名
Neuroradiology
ISSN
00283940
14321920
cat書誌ID
AA00754889
出版者
Springer Berlin Heidelberg
59
6
開始ページ
587
終了ページ
595
発行日
2017-04-10
備考
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Shu Sogabeの学位論文として提出され, 学位審査・授与の対象となっている。
This is a post-peer-review, pre-copyedit version of an article published in Neuroradiology. The final authenticated version is available online at: https://doi.org/10.1007/s00234-017-1828-9
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3134号
学位記番号
甲医第1368号
学位授与年月日
2018-03-23
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系
病院