ID | 110669 |
著者 |
アカリ, ヒロフミ
Department of Virology, The University of Tokushima School of Medicine
ヤマモト, ヨシヒコ
Department of Virology, The University of Tokushima School of Medicine
ヒワダ, ヒロコ
Department of Virology, The University of Tokushima School of Medicine
サイトウ, ヤスヨシ
Institute for Life Science Research, Asahi Chemical Industry Co. Ltd.
タカヤナギ, ノリヤス
Institute for Life Science Research, Asahi Chemical Industry Co. Ltd.
コヤマ, ハジメ
Department of Virology, The University of Tokushima School of Medicine
足立, 昭夫
Department of Virology, The University of Tokushima School of Medicine
徳島大学 教育研究者総覧
KAKEN研究者をさがす
|
キーワード | fasudil
protein kinase inhibitor
HIV-1
|
資料タイプ |
学術雑誌論文
|
抄録 | Fasudil is a potent inhibitor for various protein kinases such as myosin light chain kinase and protein kinase C. It has been used as a drug for improvement of intracranial vasospasm and following ischaemic diseases. In this report, we demonstrate that fasudil suppressed the replication of human immunodeficiency virus type 1 (HIV-1) in mitogen-activated peripheral blood mononuclear cells. Our finding shows that fasudil may be useful as a new and distinct chemotherapeutic agent against HIV-1 infection.
|
掲載誌名 |
The journal of medical investigation : JMI
|
ISSN | 13431420
|
cat書誌ID | AA11166929
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巻 | 44
|
号 | 3-4
|
開始ページ | 211
|
終了ページ | 214
|
並び順 | 211
|
発行日 | 1998
|
EDB ID | |
フルテキストファイル | |
言語 |
eng
|
著者版フラグ |
出版社版
|
部局 |
医学系
|