アクセス数 : ?
ダウンロード数 : ?
ID 106046
著者
ノセ, アユミ Department of Radiology, Tokushima University Hospital
大塚, 秀樹 Department of Radiology, Tokushima University Hospital|Department of Medical Imaging, the University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
ノセ, ハヤト Department of Radiology, Tokushima University Hospital
オトミ, ヨウイチ Department of Radiology, Tokushima University Hospital 徳島大学 教育研究者総覧 KAKEN研究者をさがす
テラザワ, カオリ Department of Radiology, Tokushima University Hospital
原田, 雅史 Department of Radiology, Tokushima University Hospital 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
201Tl-SPECT
brain tumors
retention index
differential diagnosis
資料タイプ
学術雑誌論文
抄録
Objective : To evaluate the usefulness of 201Tl-SPECT in differentiating benign from malignant brain tumors. Methods and Materials : Eighty-eight patients (44 males and 44 females) with 58 high-grade (WHO grade III-IV) and 30 low-grade (WHO grade III) tumors were evaluated with 201Tl-SPECT. (1) Visual assessment was performed by board-certificated radiologists using 201Tl-SPECT. Tumors were classified in two groups (Tl-positive and Tl-negative) and scored using the five grade evaluation system. Receiver operating characteristic (ROC) analysis was performed in the Tl-positive group. (2) Semi-quantitative assessment involved measurement of early and delayed 201Tl uptake, and the retention index (RI) was applied as follows : RI=delayed uptake ratio/early uptake ratio. Three combinations of RI using mean and maximum values of the region of interest were calculated. Results : (1) Seventy-four Tl-positive and 14 Tl-negative tumors. The area under the ROC curve (AUC) estimated by three radiologists exceeded a value of 0.7. The value was greater when estimated by the more experienced radiologist. (2) In all RIs, the difference of RI between high-grade tumors and low-grade tumors was statistically significant. Conclusion : A visual and semi-quantitative assessment using 201Tl-SPECT was found to be useful for differentiating benign from malignant brain tumors.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
60
1-2
開始ページ
121
終了ページ
126
並び順
121
発行日
2013-02
EDB ID
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院