ID 111320
著者
Terazawa, Kaori The University of Tokushima
森田, 奈緒美 The University of Tokushima
尾﨑, 享祐 The University of Tokushima
キーワード
201TlCl scintigraphy
soft tissue tumors
retention index
malignant
benign
資料タイプ
学術雑誌論文
抄録
Objective We report the findings of Thallium-201 chloride (201TlCl) scintigraphy and consider how to use this technique to evaluate the character of soft tissue lesions. Patients and Methods We enrolled 91 consecutive patients (45 males and 46 females, age range 8-91-years-old). Nineteen patients were malignant and 72 were benign. Patients were scanned 15 minutes (early phase) and 3 hours (delayed phase) after 201TlCl injection. More intense uptake in the lesion compared to the normal side was considered as ‘high’, the same degree of uptake was considered ‘iso’, and decreased uptake was ‘low’. The retention index (RI) was calculated in 9 patients in the malignant group and in 16 patients in the benign group. Results In malignant tumors, 15 of 19 patients showed high uptake in both the early and delayed phases. One malignant fibrous histiocytoma patient was high only in the delayed phase and 1 liposarcoma patient was high only in the early phase. Two liposarcoma patients showed an iso uptake in both phases. One of these patients was pathologically diagnosed as a myxoid type. In benign lesions, no lipoma showed increased uptake. All neurogenic tumors except for 2 demonstrated high uptake. All 3 ganglions of the lower extremities showed iso uptake. Most inflammatory diseases showed increased uptake. Clinically-considered benign patients consisted of tumorous lesions or inflammatory disease. Only 2 patients were considered ‘low’, and these were diagnosed as intramuscular hematoma and cyst. RI was variable in both malignant and benign lesions and no statistically significant difference was seen between malignant and benign lesions by t-test (p=0.72). Conclusions A high 201TlCl uptake lesion is more frequently seen in malignant tumors, but regardless of whether the tumor is benign or malignant, according to the histopathological variety, the 201TlCl uptake pattern can not be the only indicator to differentiate malignant from benign tumors. We ultimately need to evaluate the nature of tumors by a combination of several imaging techniques.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
56
3-4
開始ページ
136
終了ページ
141
並び順
136
発行日
2009-08
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院