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ID 116210
タイトル別表記
Reproducibility of breath-hold irradiation of lung
著者
櫻川, 加奈子 Tokushima University
Yokoishi, Michihiro Tokushima University
Tsuzuki, Akira Kochi Medical School Hospital
Sugimoto, Wataru Tokushima Prefectural Central Hospital
キーワード
dice similarity coefficient
Hausdorff distance
breath-hold irradiation
lung cancer
資料タイプ
学術雑誌論文
抄録
Methods to evaluate the positional reproducibility of breath-hold irradiation mostly require manual operation. The purpose of this study is to propose a method to determine the reproducibility of breath-hold irradiation of lung tumors between fractions using non-artificial methods. This study included 13 patients who underwent terminal exhaled breath-hold irradiation for primary and metastatic lung cancer. All subjects received a prescribed dose of 60 Gy/8 fractions. The contours of the gross tumor volume (GTV) were extracted by threshold processing using treatment-planning computed tomography (CT) and cone-beam CT (CBCT), which was done just before the beginning of the treatment. The method proposed in this study evaluates the dice similarity coefficient (DSC) and Hausdorff distance (HD) by comparing two volumes, the GTVCTS (GTV obtained from treatment-planning CT) and GTVCBCT (GTV obtained from CBCT). The reference contours for DSC and HD are represented by GTVCTS. The results demonstrated good visual agreement for cases with a DSC of ~0.7. However, apparent misalignment occurred when the DSC was <0.5. HD was >2 mm in 3 out of 13 cases, and when the DSC was ~0.7, the HD was ~1 mm. In addition, cases with greater HD also demonstrated more significant variability. It was found that the DSC and HD evaluation methods for the positional reproducibility of breath-hold irradiation proposed in this study are straightforward and can be performed without the involvement of humans. Our study is of extreme significance in the field of radiation studies.
掲載誌名
Journal of Radiation Research
ISSN
13499157
cat書誌ID
AA00705792
出版者
Oxford University Press|The Japanese Radiation Research Society|Japanese Society for Radiation Oncology
61
6
開始ページ
977
終了ページ
984
発行日
2020-09-15
権利情報
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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言語
eng
著者版フラグ
出版社版
部局
医学系