ID 111307
著者
Nishisako, Hirotaka Tokushima University
池原, 敏孝 Tokushima Bunri University
Shiraishi, Tairoh Tokushima University
Minami, Yuki Tokushima University
Ichinose(Sasaki), Hiromi Kagawa University
芳地, 一 Kagawa University
庄野, 正行 The University of Tokushima KAKEN研究者をさがす
宮本, 博司 The University of Tokushima
キーワード
eddy current
cytoskeletal protein
actin
hyposmotic stress
regulatory volume decrease
資料タイプ
学術雑誌論文
抄録
Effects of a time-varying magnetic field on cell volume regulation by hyposmotic stress in cultured bovine adrenal chromaffin cells were examined. Through regulatory volume decrease (RVD), cell volume of chromaffin cells that were incubated in a hypotonic medium initially increased, reached a peak and finally recovered to the initial value. Two hour exposure to a magnetic field and addition of cytochalasin D increased peak value and delayed return to initial value. Intracellular F-actin contents initially decreased but returned to normal levels after 10 sec. Two hour exposure to the magnetic field and addition of cytochalasin D continuously reduced the F-actin content. Results suggest that exposure to the magnetic field stimulated disruption of the actin cytoskeleton and that the disruption delayed the recovery to the volume prior to osmotic stress.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
58
1-2
開始ページ
95
終了ページ
105
並び順
95
発行日
2011-02
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
薬学系
医学系
技術支援部
理工学系