ID 109759
タイトルヨミ
シンフゼン オ ガッペイ シタ ジンケッカンセイ コウケツアツ ニ タイスル ケイヒテキ ジンドウミャク ケイセイジュツ ノ ユウコウセイ
タイトル別表記
Efficacy of percutaneous transluminal renal angioplasty for renovascular hypertension complicated with heart failure
著者
今田, 久美子 徳島大学病院卒後臨床研修センター
太田, 理絵 徳島大学病院循環器内科
門田, 宗之 徳島大学病院循環器内科
髙島, 啓 徳島大学病院循環器内科
岩瀬, 俊 徳島大学病院循環器内科 KAKEN研究者をさがす
キーワード
heart failure
cardiac disturbance syndrome
percutaneous transluminal renal angioplasty
資料タイプ
学術雑誌論文
抄録
【Background】
Percutaneous transluminal renal angioplasty (PTRA) is recommended for patients with heart failure due to renovascular hypertension ; however, the clinical characteristics of the patients and the effects of PTRA on heart failure and cardiorenal function have not been elucidated.
【Methods】
We retrospectively analyzed data for 4 PTRA-treated patients (male/female, 1/3 ; mean age, 70.0±10 years ; mean left ventricular ejection fraction, 51.5±15.2%) with heart failure due to renovascular hypertension and evaluated the effects of PTRA on heart failure and cardiorenal function 6 months after treatment.
【Results】
All patients had pro-arteriosclerotic diseases including diabetes mellitus, essential thrombocythemia, heparin cofactor II deficency, metabolic syndrome, and familial hypercholesterolemia, and 3 patients had ischemic heart disease. No abdominal bruit was heard and mean plasma renin activity was 4.5±3.6 ng/ml/hr, which was not elevated, contrary to expectation. All contralateral kidneys of PTRA were nonfunctioning, suggesting bilateral kidneys were disturbed in all patients.
In all patients, PTRA was successfully performed and resolved heart failure. PTRA resulted in decreases in systolic blood pressure from 157±18 to 124±8.6 mmHg, mean serum creatinine from 3.2±2.6 to 2.7±2.2 mg/dl, and mean BNP from 919±998 to 243±291 pg/ml at 6 months after treatment. PTRA did not change left ventricular ejection fraction, a parameter of systolic fraction evaluated by an echocardiogram ; however, PTRA improved E/e’, a parameter of left ventricular diastolic fraction, from 16.1±5.2 to 9.7±3.7. None of the patients were hospitalized due to heart failure during the 6-month period after PTRA.
【Conclusions】
Patients with heart failure with cardiovascular risk factors should be screened for renovascular hypertension regardless of abdominal bruit or plasma renin activity. PTRA is effective for resolving heart failure and for improving renal and cardiac diastolic functions in patients with renovascular hypertension complicated with heart failure.
掲載誌名
四国医学雑誌
ISSN
00373699
cat書誌ID
AN00102041
出版者
徳島医学会
70
3-4
開始ページ
87
終了ページ
92
並び順
87
発行日
2014-08-25
備考
P.91著者英語表記 : Soegi(ソエギ)は、Soeki(ソエキ)が正しいと思われる。
EDB ID
フルテキストファイル
言語
jpn
著者版フラグ
出版社版
部局
医学系
病院