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ID 118784
著者
Tomida, Satomi Kyoto Prefectural University of Medicine
Koyama, Teruhide Kyoto Prefectural University of Medicine
Ozaki, Etsuko Kyoto Prefectural University of Medicine
Takashima, Naoyuki Kyoto Prefectural University of Medicine|Shiga University of Medical Science
Morita, Midori Kyoto Prefectural University of Medicine
Sakaguchi, Koichi Kyoto Prefectural University of Medicine
Naoi, Yasuto Kyoto Prefectural University of Medicine
Nishida, Yuichiro Saga University
Hara, Megumi Saga University
Hishida, Asahi Nagoya University
Tamura, Takashi Nagoya University
Okada, Rieko Nagoya University
Kubo, Yoko Nagoya University
Otonari, Jun Kyushu University
Ikezaki, Hiroaki Kyushu University
Nakamura, Yohko Chiba Cancer Center Research Institute
Kusakabe, Miho Chiba Cancer Center Research Institute
Tanoue, Shiroh Kagoshima University
Koriyama, Chihaya Kagoshima University
Koyanagi, Yuriko N. Aichi Cancer Center Research Institute
Ito, Hidemi Aichi Cancer Center Research Institute|Nagoya University
Suzuki, Sadao Nagoya City University
Otani, Takahiro Nagoya City University
Miyagawa, Naoko Shiga University of Medical Science|Keio University
Okami, Yukiko Shiga University of Medical Science
Kuriki, Kiyonori University of Shizuoka
Wakai, Kenji Nagoya University
Matsuo, Keitaro Aichi Cancer Center|Nagoya University
キーワード
Asian population
cancer prevention
physical activity
sitting time
women's health
資料タイプ
学術雑誌論文
抄録
This study aimed to investigate the association between daily sedentary time and the risk of breast cancer (BC) in a large Japanese population. The participants were 36,023 women aged 35–69 years from the Japan Multi-Institutional Collaborative Cohort Study. Cox proportional hazards analysis was used to estimate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for BC incidence in relation to time spent sedentarily (categorical variables: <7 and ≥7 hours/day [h/d]). Additionally, the associations of BC incidence to the joint effect of sedentary time with each component of physical activity, such as leisure-time metabolic equivalents (METs), frequency of leisure-time physical activity, and daily walking time, were examined. During 315,189 person-years of follow-up, 554 incident cases of BC were identified. When compared to participants who spent <7 h/d sedentary, those who spent ≥7 h/d sedentary have a significantly higher risk of BC (HR, 1.36; 95% CI, 1.07–1.71). The corresponding HRs among participants who spent ≥7 h/d sedentary with more physical activity, such as ≥1 h/d for leisure-time METs, ≥3 days/week of leisure-time physical activity, and ≥1 h/d of daily walking were 1.58 (95% CI, 1.11–2.25), 1.77 (95% CI, 1.20–2.61), and 1.42 (95% CI, 1.10–1.83), respectively, compared with those who spent <7 h/d sedentary. This study found that spending ≥7 h/d of sedentary time is associated with the risk of BC. Neither leisure-time physical activity nor walking had a BC-preventive effect in those with ≥7 h/d of sedentary time.
掲載誌名
Cancer Science
ISSN
13497006
出版者
Japanese Cancer Association|John Wiley & Sons
115
2
開始ページ
611
終了ページ
622
発行日
2023-12-02
権利情報
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系