ID 110829
著者
ミヤモト, ヒデノリ Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
クリタ, ノブヒロ Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School KAKEN研究者をさがす
ニシオカ, マサノリ Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
アンドウ, ツトム Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School
タシロ, タカシ Department of Human Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
ヒロカワ, ミツヨシ Department of Human Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
島田, 光生 Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School 徳島大学 教育研究者総覧 KAKEN研究者をさがす
キーワード
neuroendocrine cell carcinoma
rectum
Ki-67
資料タイプ
学術雑誌論文
抄録
A 56-year-old man was admitted to our hospital because of anal bleeding. Colonoscopy and barium enema revealed type 4 tumor in the rectum. Biopsy revealed poorly differentiated adenocarcinoma. Low anterior resection with total mesorectal excision and lymph node dissection was performed. In immunohistochemical staining, chromogranin A and synaptophysin were positive at major lesion, and CEA were focal positive. The resected tumor was diagnosed pathologically as neuroendocrine cell carcinoma. The Ki-67 labeling index (LI) was 87.8%, so proliferative activity and potential malignancy was very high. Multiple metastatic tumors appeared in pelvis and lung eight months after operation. Treatment for neuroendocrine cell carcinoma of the rectum was controversial. Surgical resection and adjuvant chemotherapy might be one of the methods for gastrointestinal neruroendocrine cell carcinoma.
掲載誌名
The journal of medical investigation : JMI
ISSN
13431420
cat書誌ID
AA11166929
53
3-4
開始ページ
317
終了ページ
320
並び順
317
発行日
2006-08
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系